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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNNI3K
All Species:
13.33
Human Site:
Y125
Identified Species:
29.33
UniProt:
Q59H18
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q59H18
NP_001106279.1
936
104179
Y125
K
K
K
V
S
E
S
Y
V
I
T
I
E
R
L
Chimpanzee
Pan troglodytes
XP_513493
949
105567
Y138
K
K
K
V
S
E
S
Y
V
I
T
I
E
R
L
Rhesus Macaque
Macaca mulatta
XP_001097254
949
105560
Y138
K
K
K
V
S
E
S
Y
V
I
T
I
E
R
L
Dog
Lupus familis
XP_537112
1087
119299
Y293
K
K
K
V
S
E
S
Y
V
I
I
I
E
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5GIG6
834
92569
A76
S
L
L
H
L
C
C
A
C
G
G
N
K
S
H
Rat
Rattus norvegicus
Q7TQP6
835
92713
C77
L
L
H
L
C
C
V
C
G
G
N
K
S
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339957
835
92821
C77
L
L
H
L
C
C
I
C
G
G
N
K
A
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001021182
850
93167
K92
H
S
D
S
Q
P
E
K
L
Q
F
L
I
D
N
Sea Urchin
Strong. purpuratus
XP_782227
862
95496
C104
L
T
L
L
H
L
S
C
I
S
T
G
S
K
P
Poplar Tree
Populus trichocarpa
XP_002336079
539
60951
Maize
Zea mays
NP_001152032
543
61643
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
96.5
80.1
N.A.
80.7
81.3
N.A.
N.A.
N.A.
N.A.
75.7
N.A.
N.A.
N.A.
36.7
51.1
Protein Similarity:
100
98.3
97.2
82.6
N.A.
84.4
85.3
N.A.
N.A.
N.A.
N.A.
83.7
N.A.
N.A.
N.A.
55
65.6
P-Site Identity:
100
100
100
93.3
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
13.3
33.3
Percent
Protein Identity:
23.6
22.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
37.2
36.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
0
0
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
19
28
10
28
10
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
37
10
0
0
0
0
0
37
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
19
28
10
10
0
0
0
% G
% His:
10
0
19
10
10
0
0
0
0
0
0
0
0
19
10
% H
% Ile:
0
0
0
0
0
0
10
0
10
37
10
37
10
0
19
% I
% Lys:
37
37
37
0
0
0
0
10
0
0
0
19
10
10
0
% K
% Leu:
28
28
19
28
10
10
0
0
10
0
0
10
0
0
37
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
19
10
0
0
10
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
37
0
% R
% Ser:
10
10
0
10
37
0
46
0
0
10
0
0
19
10
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
37
0
0
0
0
% T
% Val:
0
0
0
37
0
0
10
0
37
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
37
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _